Open AccessTransient neonatal diabetes mellitus in an extremely preterm infant
Author(s) -
Shigeru Nishimaki,
Tomohide Yukawa,
Yoshio Makita,
Hidekazu Honda,
Natália Harumi Kikuchi,
Susumu Minamisawa,
Shinji Yokota
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.11.2008.1185
Subject(s) - medicine , pregnancy , diabetes mellitus , insulin , gestational diabetes , pediatrics , birth weight , obstetrics , gestation , endocrinology , genetics , biology
The present report concerns transient neonatal diabetes mellitus in an extremely preterm infant (gestational age 27 weeks, birth weight 718 g). The patient had intrauterine growth retardation and developed hyperglycaemia on the first day of life. Insulin administration was discontinued on the 89th day of life, which was 1 day before the original due date. This case suggests that (a) insufficient insulin secretion started at least from the second trimester of the pregnancy, and (b) the duration needed for recovery of insulin secretion was not dependent on the maturity.