Open AccessMalignant hypertension complicated by acute renal failure
Author(s) -
Xiao Li,
Wen Zhang,
Hua Ren,
Xiaoxia Pan,
Nan Chen
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.10.2008.1116
Subject(s) - medicine , thrombotic microangiopathy , fibrinoid necrosis , nephrosclerosis , pathology , autopsy , microangiopathy , cardiology , kidney , disease , diabetes mellitus , vasculitis , endocrinology
Malignant hypertension is closely associated with impairment of multiple organs, and renal dysfunction remains an important cause of morbidity and mortality in patients with malignant hypertension. The renal histopathological changes usually indicate malignant arteriolar nephrosclerosis (MANS) that is characterised by fibrinoid necrosis in small arteries. However, renal biopsies were not taken routinely in previous reports. We report an educational case of malignant hypertension caused by MANS leading to thrombotic microangiopathy (TMA).