Seizure or syncope? A channelopathy with cardiac and cerebral manifestation | Zendy

Christian H. Nolte | Zendy; R. Wenzel | Zendy

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Seizure or syncope? A channelopathy with cardiac and cerebral manifestation

Author(s) -

Christian H. Nolte,

R. Wenzel

Publication year - 2009

Publication title -

bmj case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.231

H-Index - 26

ISSN - 1757-790X

DOI - 10.1136/bcr.10.2008.1024

Subject(s) - channelopathy , medicine , short qt syndrome , syncope (phonology) , consciousness , cardiology , levetiracetam , long qt syndrome , epilepsy , sudden cardiac death , anesthesia , qt interval , psychiatry , neuroscience , biology

A 24-year-old woman was diagnosed with long QT syndrome (LQTS) because of recurring losses of consciousness. She was implanted with a cardioverter-defibrillator, but losses of consciousness reoccurred. Genetic analysis proved LQTS. An electroencephalogram showed spontaneous generalised spikes and polyspike waves with a 3-4/s frequency. Losses of consciousness ceased only after antiepileptic treatment. We conclude that it may by worthwhile scrutinising patients with LQTS for subtle epileptic activity to find evidence for a cerebral manifestation of a disease thought to be confined to the heart.

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