Open AccessAcute hepatitis induced by glatiramer acetate
Author(s) -
Pierre Deltenre,
Marie-Odile Peny,
André Dufour,
Mohamed M. El Nady,
Jean Henrion
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.09.2008.0913
Subject(s) - medicine , glatiramer acetate , acute hepatitis , hepatitis , intensive care medicine , multiple sclerosis , pharmacology , immunology
Glatiramer acetate, a mixture of synthetic polypeptides able to prevent autoimmune encephalomyelitis in experimental models, is used as a treatment for patients with active relapsing-remitting multiple sclerosis. We report one case of glatiramer acetate induced hepatitis. Liver biopsy was consistent with a diagnosis of drug induced hepatitis and alanine aminotransferase returned to normal values after treatment discontinuation. The present case should serve as a warning that glatiramer acetate may cause acute liver disease.