Open AccessCorticobasal syndrome due to a thalamic tuberculoma and focal cortical atrophy
Author(s) -
Kandadai Rukmini Mridula,
S Alladi,
Dandu Ravi Varma,
Jaydip Ray Chaudhuri,
Jyotsna Yarlagadda,
Rupam Borgohain,
Subhash Kaul
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.08.2008.0820
Subject(s) - corticobasal degeneration , tuberculoma , medicine , posterior cortical atrophy , atrophy , apraxia , pathology , neuroscience , progressive supranuclear palsy , dementia , disease , psychology , aphasia , psychiatry , tuberculosis
Corticobasal syndrome (CBS) is characterised by asymmetric apraxia, cortical sensory loss, extrapyramidal features and cognitive decline. Although CBS is classically described as a taupathy, heterogeneity of its aetiology is increasingly recognised. Clinical presentation of CBS appears to reflect areas of the brain involved and not necessarily the nature of the underlying pathology. We report a patient in whom resolution of a thalamic tuberculoma was associated with progressive atrophy of the parietotemporal cortex, resulting in an unusual presentation of CBS.