Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: is exercise the cause? | Zendy

Gregory P. Whyte | Zendy; Mary N. Sheppard | Zendy; Keith George | Zendy; Rob Shave | Zendy; Sanjay Prasad | Zendy; Rory O’Hanlon | Zendy; Sanjay Sharma | Zendy

Open Access

Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: is exercise the cause?

Author(s) -

Gregory P. Whyte,

Mary N. Sheppard,

Keith George,

Rob Shave,

Sanjay Prasad,

Rory O’Hanlon,

Sanjay Sharma

Publication year - 2009

Publication title -

bmj case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.231

H-Index - 26

ISSN - 1757-790X

DOI - 10.1136/bcr.08.2008.0758

Subject(s) - medicine , ventricle , cardiology , pathological , muscle hypertrophy , myocardial fibrosis , fibrosis , myocardial hypertrophy , left ventricular hypertrophy , blood pressure

We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.

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