Open AccessTreatment of Buerger disease (thromboangiitis obliterans) with bosentan: a case report
Author(s) -
Joaquín De Haro,
Aurora Martínez Flórez,
José Luis Fernández Fernández,
Francisco Acín
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.08.2008.0691
Subject(s) - bosentan , buerger's disease , medicine , discontinuation , endothelin receptor antagonist , disease , dermatology , surgery , cardiology , endothelin receptor , receptor
Buerger disease (thromboangiitis obliterans) is a non-atherosclerotic segmental inflammatory disease strongly associated with tobacco use, and it affects small and medium-sized blood vessels in the upper and lower extremities. The only known treatment for this disease is complete discontinuation of tobacco use. This report describes the case history of a woman with Buerger disease treated with the oral dual endothelin receptor antagonist bosentan. It is believed that this is the first description in the literature of this use for bosentan.