Open AccessIncontinence and mood disorder: is there an association?
Author(s) -
Kamini Vasudev,
Arun Kumar Gupta
Publication year - 2010
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.07.2009.2118
Subject(s) - aripiprazole , medicine , depression (economics) , reboxetine , urinary incontinence , psychiatry , major depressive disorder , mood disorders , mood , urology , schizophrenia (object oriented programming) , antidepressant , reuptake inhibitor , anxiety , economics , macroeconomics
A variety of psychiatric disorders including depression have been reported in patients suffering from incontinence. It is uncertain if the association between incontinence and depression is causal or is related to a third common factor. We report the case of a 48-year-old man who presented with incontinence of urine and faeces along with a severe depressive episode. No organic cause could be identified for the incontinence. The depressive symptoms as well as the incontinence resolved with treatment with reboxetine and aripiprazole. However, the patient developed a manic episode. This case supports the hypothesis that incontinence and depression may share a common pathogenesis. The authors review the literature to investigate this linkage. The combination of aripiprazole and reboxetine should be used cautiously when treating first episode depression as it can induce a manic switch. Previous reports of manic switch with aripiprazole and reboxetine are reviewed.