Open AccessCollision of advanced gastric adenocarcinoma and gastrointestinal stromal tumour: a case report
Author(s) -
Akihiro Toyoda,
Akira Komaba,
Hiroaki Yoshizumi,
Ryosuke Hanaoka,
Syoko Sakuma,
Akira Ichinohe,
Hiroki Kawana,
Kenichi Harigaya
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.07.2009.2075
Subject(s) - gist , medicine , histogenesis , cancer , adenocarcinoma , stomach , stromal tumor , gastroenterology , pathology , stromal cell , oncology , immunohistochemistry
We present a case of an 83-year-old female patient with a collision tumour of an advanced Borrmann type 4 gastric cancer and a large gastric gastrointestinal stromal tumour (GIST). According to the deformity of the gastric wall caused by the GIST, type 4 cancer was difficult to identify by oesophagogastroduodenoscopy (OGD). The patient died of progressive gastric cancer related disease. While the mechanism of histogenesis of the simultaneous adenocarcinoma and GIST remains to be determined, the present case suggests that gastric adenocarcinoma has a more adverse effect on prognosis than does GIST. Additionally, this case suggests that thorough inspection of GIST patients is required at the OGD and at the pathology facility, in order to avoid overlooking the underlying cancer.