Open AccessReversible limbic encephalitis with antibodies against the membranes of neurones of the hippocampus
Author(s) -
Hideyuki Shimazaki,
Yumiko Ando,
Imaharu Nakano,
Josep Dalmau
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.07.2008.0509
Subject(s) - limbic encephalitis , medicine , plasmapheresis , hippocampus , antibody , encephalitis , pathology , neurology , immunology , virus , autoantibody , psychiatry
The authors report a patient with limbic encephalitis associated with an ovarian teratoma. An antibody against the membranes of neurones of the hippocampus was identified in both serum and CSF. Immunosuppressive treatments such as plasmapheresis and high-dose intravenous immunoglobulin administration resulted in a rapid clinical recovery.