Open AccessPost liver transplant tuberculosis
Author(s) -
Luís Vaz Rodrigues,
Judit Gandara,
João Valter Pires,
Raquel Duarte,
Fernando Calvário,
Miguel Domínguez,
Aurora Carvalho,
R. Seca
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.05.2009.1847
Subject(s) - medicine , immunosuppression , tuberculosis , context (archaeology) , liver transplantation , liver toxicity , liver enzyme , drug , pulmonary tuberculosis , intensive care medicine , toxicity , immunology , pharmacology , transplantation , pathology , paleontology , biology
We report on a patient diagnosed with disseminated (hepatic and pulmonary) tuberculosis in the context of immunosuppression following liver transplant. During the administration of anti-tuberculosis drugs an abrupt elevation of liver enzymes was detected leading us to suspect drug toxicity rather than graft rejection. Nevertheless, careful surveillance and adjustment of serum levels of immunosuppressant drugs permitted continuance of tuberculosis treatment with no further side effects.