Open AccessManagement of immune thrombocytopoenia in a patient with newly-diagnosed smouldering myeloma and colorectal cancer
Author(s) -
Agostina Siniscalchi,
Roberto Stasi,
Stefano Fratoni,
Paolo de Fabritiis,
Tommaso Caravita
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.03.2009.1715
Subject(s) - medicine , asymptomatic , colorectal cancer , rituximab , multiple myeloma , lymphoproliferative disorders , lymphoma , cancer , oncology
Immune thrombocytopoenia (ITP) is one of the most common autoimmune manifestations of B cell lymphoproliferative diseases. The association with multiple myeloma (MM) and solid tumours is rare. Here, a case of ITP associated with asymptomatic multiple myeloma and colon carcinoma, refractory to standard therapy and responsive to rituximab, is described. ITP should be considered in the differential diagnosis of thrombocytopoenia in MM and colon cancer. Understanding of the potential risk and reversibility of ITP should aid in the management of these patients.