Management of immune thrombocytopoenia in a patient with newly-diagnosed smouldering myeloma and colorectal cancer | Zendy

Antonio Daniele Pinna | Zendy; Roberto Stasi | Zendy; Stefano Fratoni | Zendy; Paolo de Fabritiis | Zendy; T. Caravita | Zendy

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Management of immune thrombocytopoenia in a patient with newly-diagnosed smouldering myeloma and colorectal cancer

Author(s) -

Antonio Daniele Pinna,

Roberto Stasi,

Stefano Fratoni,

Paolo de Fabritiis,

T. Caravita

Publication year - 2009

Publication title -

bmj case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.231

H-Index - 26

ISSN - 1757-790X

DOI - 10.1136/bcr.03.2009.1715

Subject(s) - medicine , asymptomatic , colorectal cancer , rituximab , multiple myeloma , lymphoproliferative disorders , lymphoma , cancer , oncology

Immune thrombocytopoenia (ITP) is one of the most common autoimmune manifestations of B cell lymphoproliferative diseases. The association with multiple myeloma (MM) and solid tumours is rare. Here, a case of ITP associated with asymptomatic multiple myeloma and colon carcinoma, refractory to standard therapy and responsive to rituximab, is described. ITP should be considered in the differential diagnosis of thrombocytopoenia in MM and colon cancer. Understanding of the potential risk and reversibility of ITP should aid in the management of these patients.

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