Open AccessPrecocious puberty and a sellar mass
Author(s) -
Anil Bhansali,
Petrilla Jayaprakash,
Pinaki Dutta,
Rama Walia,
Pushpa Ravikumar
Publication year - 2009
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr.03.2009.1677
Subject(s) - medicine , precocious puberty , levothyroxine , etiology , endocrinology , pediatrics , pituitary disorder , hormone
Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for neurosurgical intervention to our institute. On investigation, she was found to have primary hypothyroidism of autoimmune aetiology, which is rarely associated with precocious puberty and sellar mass due to thyrotroph hyperplasia. She was successfully treated with levothyroxine, and with this secondary sexual characteristics progressively regressed and the sellar mass disappeared.