Open AccessAdult-onset Still’s disease with concurrent thrombotic thrombocytopenic purpura: case report and literature review
Author(s) -
Ryohei Kato,
Tomoyuki Ikeuchi,
Katsuyuki Tomita,
Akira Yamasaki
Publication year - 2020
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2020-235786
Subject(s) - medicine , thrombotic thrombocytopenic purpura , septic shock , complication , rare disease , ferritin , pediatrics , disease , purpura (gastropod) , shock (circulatory) , dermatology , gastroenterology , sepsis , platelet , ecology , biology
Thrombotic thrombocytopenic purpura (TTP) is rare complication resulting from adult-onset Still's disease (AOSD). We report the case of a 69-year-old Japanese man who initially presented with fever and joint pain and was diagnosed as having concurrent AOSD with TTP 1 month later. He had extremely high ferritin levels (32 696 ng/mL). He initially responded to plasma exchange but subsequently died of septic shock. AOSD accompanied by extremely high ferritin levels might be considered a sign of concurrent TTP.