
Paediatric severe chronic spontaneous urticaria: successful management through conventional drug therapy
Author(s) -
Dimitri Poddighe,
Ilaria Brambilla,
Amelia Licari,
Gian Luigi Marseglia
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2019-230925
Subject(s) - medicine , atopy , drug , dermatology , intensive care medicine , comorbidity , cetirizine , allergy , pediatrics , immunology , pharmacology
Chronic spontaneous urticaria (CSU) can occur in children and the clinical management is quite challenging. Here, we described a paediatric clinical case of CSU successfully managed by conventional therapy, including systemic steroids, cetirizine, anti-leukotriene drug and dietary restriction (for histamine-releasing foods). This patient showed neither atopy nor any allergic sensitisation; moreover, the autologous serum skin test resulted negative. This category of patients with no comorbidity and no evidence of atopy might benefit from the conventional drug management; however, a protracted course of steroid treatment with very slow and gradual tapering may be needed. This approach was successful and safe in our clinical case, but a careful follow-up, due to the potential side effects of steroids, should be recommended.