Open AccessSystemic lupus erythematosus and melioidosis
Author(s) -
Mohd Jazman Che Rahim,
Nurashikin Mohammad,
Muhammad Imran Kamaruddin,
Wan Syamimee Wan Ghazali
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2019-229974
Subject(s) - medicine , melioidosis , septic shock , intensive care unit , sepsis , cyclophosphamide , burkholderia pseudomallei , systemic lupus erythematosus , respiratory failure , shock (circulatory) , intensive care medicine , disease , chemotherapy , pathology , biology , bacteria , genetics
We reported a case of a young female patient presented with sepsis and diagnosed with melioidosis and systemic lupus erythematosus (SLE) within the same admission. She presented with 1-week history of productive cough, progressive dyspnoea together with prolonged fever, arthralgia, rashes and oral ulcers. She had septicemic shock, respiratory failure requiring intubation and ventilation in intensive care unit and subsequently developed acute renal failure requiring haemodialysis. Antibiotics and immunosuppressive treatment including low-dose intravenous cyclophosphamide were commenced. She had a remarkable recovery and was discharged after 6 weeks. There was no evidence of active SLE or relapse of melioidosis during clinic follow-ups.