Open AccessRevealing a rare inflammatory oral manifestation in a 6-year-old child
Author(s) -
Samapika Routray,
Amit Kumar Adhya,
Joseph John,
Punit Singh Dikhit
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2019-229483
Subject(s) - medicine , buccal mucosa , langerhans cell histiocytosis , molar , oral and maxillofacial surgery , biopsy , dermis , pathology , dermatology , buccal administration , rare disease , oral mucosa , dentistry , disease , oral cavity
A 6-year-old child with an episodic history of ulcerations over buccal mucosa was found to have severe inflammation on the palatal aspect of permanent first molars with grade 2 mobility bilaterally. Radiographical features were suggestive of bone loss around permanent molars extending to the distal aspect of the deciduous first molars. The clinical and radiographical findings were indicative of periodontal degeneration without any apparent cause visible intraorally. Further biopsy was done from the rashes present on the malar prominences, which showed nodular aggregates of atypical cells in superficial dermis. These large histiocytic cells with vesicular nuclei and nuclear grooves were immunopositive for CD1a and S100, concluding the diagnosis of Langerhans cell histiocytosis. For treatment, patient was referred to Department of Haemato-oncology and chemotherapy was suggested as per protocol.