Open AccessMacitentan in the treatment of severe digital ulcers
Author(s) -
Tatiana Gonçalves,
Lèlita Santos
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2018-228295
Subject(s) - medicine , refractory (planetary science) , dermatology , astrobiology , physics
Digital ulcers are one of the earliest and most disabling manifestations of systemic sclerosis (SSc). We report the clinical case of a female patient with SSc and severe digital ulcers, recurrent and refractory to the classic treatments to whom it was prescribed off-label macitentan with complete resolution of the condition.