Open AccessCase of autoimmune polyglandular syndrome type 2: how we uncovered the diagnosis
Author(s) -
Akhila Arya P,
Jyoti Kumar,
Dileep Unnikrishnan,
Rishi Raj
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2018-227187
Subject(s) - medicine , vitiligo , etiology , pediatrics , medical history , physical examination , autoimmune thyroiditis , vomiting , adrenal insufficiency , past medical history , thyroiditis , nausea , disease , dermatology
A 24-year-old man with no significant medical history presented to the medical clinic with vomiting and giddiness for 2 days, loss of appetite for 1 month and progressive fatigability for the preceding 4 months. On examination, he was found to be hypotensive and was admitted to the hospital for work-up. Considering his abnormal labs and physical findings, he was worked up and was diagnosed with primary adrenal insufficiency. On further work-up for the aetiology of his Addison's disease, he was found to have concurrent autoimmune thyroiditis and vitiligo. A final diagnosis of autoimmune polyglandular syndrome type 2 was made. The patient was started on hormone replacement therapy and reported improvement of symptoms on 3-month follow-up visit.