Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy | Zendy

Marian L. Dale | Zendy; Deniz ErtenLyons | Zendy; Frank Bittner | Zendy; Randy Woltjer | Zendy

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Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy

Author(s) -

Marian L. Dale,

Deniz ErtenLyons,

Frank Bittner,

Randy Woltjer

Publication year - 2018

Publication title -

bmj case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.231

H-Index - 26

ISSN - 1757-790X

DOI - 10.1136/bcr-2018-227119

Subject(s) - progressive supranuclear palsy , pathology , medicine , tauopathy , meningoencephalitis , pathological , cerebrospinal fluid , dementia , central nervous system , white matter , neurology , disease , magnetic resonance imaging , radiology , neurodegeneration , psychiatry

We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue.

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