Open AccessLevosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis
Author(s) -
Devashish Desai,
Kartik Gupta,
Rohit Kumar,
Ashutosh Biswas
Publication year - 2018
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2018-224679
Subject(s) - medicine , neuroleptic malignant syndrome , bromocriptine , rheumatoid arthritis , malignant hyperthermia , vomiting , diabetes mellitus , arthritis , pediatrics , anesthesia , surgery , endocrinology , hormone , prolactin
A 53-year-old woman, known case of diabetes mellitus and rheumatoid arthritis, presented with a 4-day history of hyperthermia, rigidity, tremor and altered sensorium. She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency. We managed her as a case of life-threatening neuroleptic malignant syndrome (NMS) requiring mechanical ventilation, bromocriptine and other supportive care. She subsequently recovered and was discharged in a stable condition. To the best of our knowledge, this is the first documented case report describing levosulpiride-induced NMS.