Open AccessParaneoplastic cerebellar degeneration as a manifestation of metastatic recurrent carcinoma breast: rare scenario
Author(s) -
Shivangi Saha,
Alok Kumar,
Chitresh Kumar,
Kamal Kataria
Publication year - 2018
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2017-222575
Subject(s) - medicine , trastuzumab , rare disease , breast carcinoma , axilla , mastectomy , paraneoplastic cerebellar degeneration , prednisolone , axillary lymph node dissection , metastasis , adjuvant therapy , radiology , breast cancer , disease , pathology , surgery , chemotherapy , cancer , sentinel lymph node , antibody , immunology , autoantibody
Carcinoma breast presenting with paraneoplastic cerebellar degeneration is a rare scenario. We report a case of a 52-year-old woman, which is a follow-up case of completely treated carcinoma breast presenting with paraneoplastic cerebellar degeneration which, on investigation, revealed metastatic disease with recurrence at previous scar site and metastasis to contralateral axilla. The patient was given pulse methyl prednisolone therapy and underwent wide local excision of nodule and right axillary lymph node dissection with 14 cycles of trastuzumab and paclitaxel as adjuvant therapy. However, there was no detectable change in neurological symptoms at 6-month follow-up postoperatively. This case report highlights the need for clinicians to be aware of all possible presentations of carcinoma breast and its recurrence, including rare manifestations as in this case.