Open AccessNative valveProteus mirabilisendocarditis: successful treatment of a rare entity formulated by in vitro synergy antibiotic testing
Author(s) -
Caroline R Brotzki,
Kari A. Mergenhagen,
Zackery P. Bulman,
Brian T. Tsuji,
Charles S. Berenson
Publication year - 2016
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2016-215956
Subject(s) - medicine , proteus mirabilis , endocarditis , antibiotics , rare disease , proteus , microbiology and biotechnology , in vitro , intensive care medicine , bacteria , staphylococcus aureus , biology , disease , biochemistry , escherichia coli , gene , genetics
Infective endocarditis caused by Proteus mirabilis is a rare and poorly reported disease, with no well-defined effective antibiotic regimen. Here, we present a case of P. mirabilis aortic valve endocarditis. We reviewed prior cases and treatment regimens, and devised effective treatment, which was guided by in vitro sensitivity and synergy testing on the pathogen. Our patient survived without complications or the need for a surgical intervention.