Open AccessAbsence of relationship between serum cortisol and critical illness in premature infants
Author(s) -
Irina Prelipcean,
James L. Wynn,
Lindsay A. Thompson,
David J. Burchfield,
Laurence James-Woodley,
Philip B Chase,
Charles D. Barnes,
Angelina Bernier
Publication year - 2021
Publication title -
archives of disease in childhood. fetal and neonatal edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.957
H-Index - 116
eISSN - 1468-2052
pISSN - 1359-2998
DOI - 10.1136/archdischild-2020-319970
Subject(s) - medicine , gestational age , illness severity , hydrocortisone , neonatal intensive care unit , adrenal insufficiency , glucocorticoid , population , pediatrics , cohort , severity of illness , intensive care , critical illness , retrospective cohort study , univariate analysis , pregnancy , critically ill , multivariate analysis , intensive care medicine , genetics , environmental health , biology
Inadequate cortisol production in response to critical illness in extremely preterm infants may exacerbate poor outcomes. Despite commonly measuring cortisol concentration and administering hydrocortisone for presumed adrenal insufficiency, the relationship between serum cortisol concentration and illness severity remains unclear in this unique population.