Open AccessB cell subset composition segments clinically and serologically distinct groups in chronic cutaneous lupus erythematosus
Author(s) -
Scott A. Jenks,
Chungwen Wei,
Regina Bugrovsky,
April T Hill,
Xiaoqian Wang,
Francesca Maria Rossi,
Kevin S. Cashman,
Matthew C. Woodruff,
Laura Aspey,
S Sam Lim,
Gaobin Bao,
Cristina Drenkard,
Igñacio Sanz
Publication year - 2021
Publication title -
annals of the rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.333
H-Index - 240
eISSN - 1468-2060
pISSN - 0003-4967
DOI - 10.1136/annrheumdis-2021-220349
Subject(s) - medicine , systemic lupus erythematosus , immunology , autoantibody , b cell , antibody , serology , lupus erythematosus , disease , pathology
While the contribution of B-cells to SLE is well established, its role in chronic cutaneous lupus erythematosus (CCLE) remains unclear. Here, we compare B-cell and serum auto-antibody profiles between patients with systemic lupus erythematosus (SLE), CCLE, and overlap conditions.