Open AccessGlobal skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile
Author(s) -
Brian Skaug,
Dinesh Khanna,
William R. Swindell,
Monique Hinchcliff,
Tracy Frech,
Virginia Steen,
Faye N. Hant,
Jessica Gordon,
Ami A. Shah,
Lisha Zhu,
W. Jim Zheng,
Jeffrey L. Browning,
Alex Barron,
Minghua Wu,
Sudha Visvanathan,
Patrick Baum,
Jennifer Franks,
Michael L. Whitfield,
Victoria K. Shanmugam,
Robyn T. Domsic,
Flavia V. Castelino,
Elana J. Bernstein,
Nancy Wareing,
Marka A. Lyons,
Ying Jin,
Julio Charles,
Maureen D. Mayes,
Shervin Assassi
Publication year - 2019
Publication title -
annals of the rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.333
H-Index - 240
eISSN - 1468-2060
pISSN - 0003-4967
DOI - 10.1136/annrheumdis-2019-215894
Subject(s) - medicine , immune system , skin biopsy , pathology , scleroderma (fungus) , biopsy , innate immune system , immunology , acquired immune system , cohort , systemic disease , disease , inoculation
Determine global skin transcriptome patterns of early diffuse systemic sclerosis (SSc) and how they differ from later disease.