Open AccessIncreased risk of rheumatoid arthritis among mothers with children who carryDRB1risk-associated alleles
Author(s) -
Giovanna Cruz,
Xiaorong Shao,
Hong Quach,
Kimberly A Ho,
Kirsten Sterba,
Janelle A. Noble,
Nikolaos A. Patsopoulos,
Michael P. Busch,
Darrell J. Triulzi,
Wendy S. W. Wong,
Benjamin D. Solomon,
John E. Niederhuber,
Lindsey A. Criswell,
Lisa F. Barcellos
Publication year - 2017
Publication title -
annals of the rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.333
H-Index - 240
eISSN - 1468-2060
pISSN - 0003-4967
DOI - 10.1136/annrheumdis-2016-210662
Subject(s) - medicine , valine , allele , genotype , rheumatoid arthritis , gastroenterology , pediatrics , genetics , amino acid , biology , gene
To investigate whether a child's genotype affects a mother's risk of rheumatoid arthritis (RA) beyond the risk associated with her genotype and to test whether exposure to fetal alleles inherited from the father increases risk of RA among mothers without risk alleles.