Open AccessReal-Life Feasibility of HIV Drug Resistance Testing Using Dried Filter Analytes in Kenyan Children and Adolescents Living with HIV
Author(s) -
Akarsh Manne,
Alexander DeLong,
Winstone Nyandiko,
Allison DeLong,
Rachel C. Vreeman,
Vladimir Novitsky,
Anthony Ngeresa,
Edwin Sang,
Ashley Chory,
Josephine Aluoch,
Eslyne Jepkemboi,
Millicent Orido,
Celestine Ashimosi,
Festus Sang,
Joseph W. Hogan,
Rami Kantor
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
ISSN - 2165-0497
DOI - 10.1128/spectrum.02675-21
Subject(s) - genotyping , hiv drug resistance , kenya , medicine , viral load , human immunodeficiency virus (hiv) , drug resistance , logistic regression , dried blood spot , immunology , antiretroviral therapy , biology , genotype , ecology , microbiology and biotechnology , biochemistry , genetics , gene
In this manuscript we use dried filter analytes shipped from Kenya to the US in real time, to demonstrate the real-life feasibility of conducting HIV drug resistance testing in a vulnerable population of young children and adolescents with HIV in a resource limited setting. Such testing, which is recommended in resource-rich settings, is unavailable in most resource limited settings for individual clinical care.