A Feasible Alternative Strategy Targeting Furin Disrupts SARS-CoV-2 Infection Cycle | Zendy

Tanmoy Mondal | Zendy; Gururaj Shivange | Zendy; Alaa Habieb | Zendy; Jogender TushirSingh | Zendy

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A Feasible Alternative Strategy Targeting Furin Disrupts SARS-CoV-2 Infection Cycle

Author(s) -

Tanmoy Mondal,

Gururaj Shivange,

Alaa Habieb,

Jogender TushirSingh

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.02364-21

Subject(s) - furin , protease , biology , coronavirus , viral entry , virology , cleavage (geology) , virus , microbiology and biotechnology , biochemistry , enzyme , covid-19 , viral replication , medicine , infectious disease (medical specialty) , paleontology , pathology , fracture (geology) , disease

Since its emergence in December 2019, COVID-19 has remained a global economic and health threat. Although RNA and DNA vector-based vaccines induced antibody response and immunological memory have proven highly effective against hospitalization and mortality, their long-term efficacy remains unknown against continuously evolving SARS-CoV-2 variants.

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