Open AccessThe Type IV Pilus of Plasmid TP114 Displays Adhesins Conferring Conjugation Specificity and Is Important for DNA Transfer in the Mouse Gut Microbiota
Author(s) -
Nancy Allard,
Kevin Neil,
Frédéric Grenier,
Sébastien Rodrigue
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.502
H-Index - 51
ISSN - 2165-0497
DOI - 10.1128/spectrum.02303-21
Subject(s) - plasmid , pilus , horizontal gene transfer , biology , bacterial adhesin , gene , bacterial genetics , genetics , bacteria , microbiology and biotechnology , dna , gut flora , gene transfer , bacterial conjugation , antibiotic resistance , escherichia coli , genome , immunology
Conjugative plasmids are involved in horizontal gene transfer in the gut microbiota, which constitutes an important antibiotic resistance gene reservoir. However, the molecular mechanisms used by conjugative plasmids to select recipient bacteria and transfer at high rates in the mouse gut microbiota remain poorly characterized.