Open AccessCandida albicans END3 Mediates Endocytosis and Has Subsequent Roles in Cell Wall Integrity, Morphological Switching, and Tissue Invasion
Author(s) -
Christiane Rollenhagen,
Harrison Agyeman,
Susan K. Eszterhas,
Samuel A. Lee
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.502
H-Index - 51
ISSN - 2165-0497
DOI - 10.1128/spectrum.01880-21
Subject(s) - endocytosis , candida albicans , microbiology and biotechnology , cell , biology , genetics
Candida albicans is a fungal commensal organism that can cause serious opportunistic infections in immunocompromised patients leading to substantial complications and mortality. A better understanding of the microbe’s biology to develop more effective therapeutic and diagnostic tools is required as invasive candidiasis is a problem of continued clinical importance.
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