Open AccessInternal Transcription Terminators Control Stoichiometry of ABC Transporters in Cellulolytic Clostridia
Author(s) -
Shenshen Wu,
Mengcheng You,
Na Wang,
Zhenxing Ren,
Chenggang Xu
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.502
H-Index - 51
ISSN - 2165-0497
DOI - 10.1128/spectrum.01656-21
Subject(s) - operon , atp binding cassette transporter , biology , gene , genetics , pseudogene , transcription (linguistics) , clostridia , intergenic region , regulation of gene expression , computational biology , mutant , transporter , bacteria , linguistics , philosophy , genome
Operons encoding protein complexes or metabolic pathways usually require fine-tuned gene expression ratios to create and maintain the appropriate stoichiometry for biological functions. In this study, a strategy for controlling differential expression of genes in an operon was proposed by utilizing ABC importers fromRuminiclostridium cellulolyticum .