Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens | Zendy

Jing Song | Zendy; Weili Du | Zendy; Zichen Liu | Zendy; Jialu Che | Zendy; Kun Li | Zendy; Nanying Che | Zendy

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Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens

Author(s) -

Jing Song,

Weili Du,

Zichen Liu,

Jialu Che,

Kun Li,

Nanying Che

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.01358-21

Subject(s) - amplicon , tuberculosis , computational biology , drug resistant tuberculosis , drug , drug resistance , mycobacterium tuberculosis , biology , medicine , genetics , polymerase chain reaction , pharmacology , pathology , gene

Amplicon-based targeted NGS technology focuses on a set of gene mutations of known or suspected associations with drug susceptibility inMycobacterium tuberculosis (MTB). This method offers many benefits, such as low sequencing cost, easy customization, high throughput, shorter testing time and not culture dependent.

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