Sub-Inhibitory Concentrations of Oxacillin, but Not Clindamycin, Linezolid, or Tigecycline, Decrease Staphylococcal Phenol-Soluble Modulin Expression in Community-Acquired Methicillin-Resistant Staphylococcus aureus | Zendy

Elisabeth Hodille | Zendy; Laetitia Béraud | Zendy; Séverine Perian | Zendy; Valentine Berti | Zendy; Michèle Bes | Zendy; Anne Tristan | Zendy; Emilie Blond | Zendy; Gérard Lina | Zendy; Oana Dumitrescu | Zendy

Open Access

Sub-Inhibitory Concentrations of Oxacillin, but Not Clindamycin, Linezolid, or Tigecycline, Decrease Staphylococcal Phenol-Soluble Modulin Expression in Community-Acquired Methicillin-Resistant Staphylococcus aureus

Author(s) -

Elisabeth Hodille,

Laetitia Béraud,

Séverine Perian,

Valentine Berti,

Michèle Bes,

Anne Tristan,

Emilie Blond,

Gérard Lina,

Oana Dumitrescu

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.00808-21

Subject(s) - linezolid , microbiology and biotechnology , clindamycin , tigecycline , antibiotics , staphylococcus aureus , toxin , biology , chemistry , vancomycin , bacteria , genetics

Staphylococcal toxins play an important role in the physiopathology of staphylococcal infections. Subinhibitory concentrations (sub-MIC) of antibiotics modulatein vitro toxins expression inS. aureus : clindamycin (CLI) and linezolid (LIN) display an anti-toxin effect on Panton-Valentine leucocidin and alpha-hemolysin production, while oxacillin (OXA) has an inducing effect.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research