Open AccessIdentification of Small Molecule Inhibitors of the Pathogen Box against Vibrio cholerae
Author(s) -
Haeun Kim,
Brianne J. Burkinshaw,
Linh Lam,
Kevin Manera,
Tao Dong
Publication year - 2021
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
ISSN - 2165-0497
DOI - 10.1128/spectrum.00739-21
Subject(s) - vibrio cholerae , cholera , microbiology and biotechnology , pathogen , biology , antibiotics , antibiotic resistance , vibrionaceae , efflux , bacteria , genetics
Cholera is a serious infectious disease in tropical regions causing millions of infections annually.Vibrio cholerae , the causative agent of cholera, has gained multi-antibiotic resistance over the years, posing greater threat to public health and current treatment strategies. Here we report two compounds that effectively target the growth ofV. cholerae and have the potential to control cholera infection.