Open AccessGenomic Characteristics of Recently Recognized Vibrio cholerae El Tor Lineages Associated with Cholera in Bangladesh, 1991 to 2017
Author(s) -
Md Mamun Monir,
Talal Hossain,
Masatomo Morita,
Makoto Ohnishi,
Fatema-Tuz Johura,
Marzia Sultana,
Shirajum Monira,
Tahmeed Ahmed,
Nicholas R. Thomson,
Haruo Watanabe,
Anwar Huq,
Rita R. Colwell,
Kimberley D. Seed,
Munirul Alam
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.502
H-Index - 51
ISSN - 2165-0497
DOI - 10.1128/spectrum.00391-22
Subject(s) - biology , vibrio cholerae , genetics , genome , cholera , el tor , lineage (genetic) , single nucleotide polymorphism , comparative genomics , gene , genomics , virology , genotype , bacteria
Cholera is a global disease with specific reference to the Bay of Bengal Ganges Delta whereVibrio cholerae O1 El Tor, the causative agent of the disease showed two circulating lineages, one dominant in Bangladesh and the other in India. Results of an in-depth genomic study ofV. cholerae associated with endemic cholera during the past 27 years (1991 to 2017) indicate emergence and succession of the two lineages, BD-1 and BD-2, arising from a common ancestral paraphyletic group, BD-0, comprising the early strains and short-term evolution of the bacterium in Bangladesh.