Open AccessRole of Extracellular DNA in Dalbavancin Activity against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms in Patients with Skin and Soft Tissue Infections
Author(s) -
Francesca Sivori,
Ilaria Cavallo,
Daniela Kovacs,
María Guembe,
Isabella Sperduti,
Mauro Truglio,
Martina Pasqua,
G. Prignano,
Arianna Mastrofrancesco,
Luigi Toma,
Fulvia Pimpinelli,
Aldo Morrone,
Fabrizio Ensoli,
Enea Gino Di Domenico
Publication year - 2022
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
ISSN - 2165-0497
DOI - 10.1128/spectrum.00351-22
Subject(s) - dalbavancin , staphylococcus aureus , methicillin resistant staphylococcus aureus , staphylococcal skin infections , microbiology and biotechnology , soft tissue , medicine , staphylococcal infections , skin infection , biofilm , vancomycin , biology , bacteria , surgery , genetics
Staphylococcus aureus is the most common cause of skin and soft tissue infections (SSTIs) worldwide. In addition, methicillin-resistantS. aureus (MRSA) is increasingly frequent in postoperative infections and responsible for a large number of hospital readmissions and deaths.