Retrospective Evaluation of Various Serological Assays and Multiple Parameters for Optimal Diagnosis of Lyme Neuroborreliosis in a Routine Clinical Setting | Zendy

Tamara van Gorkom | Zendy; Willem Voet | Zendy; Gijs H. J. van Arkel | Zendy; Michiel Heron | Zendy; B. J. A. Hoeve-Bakker | Zendy; Daan W. Notermans | Zendy; Steven Thijsen | Zendy; Kristin Kremer | Zendy

Open Access

Retrospective Evaluation of Various Serological Assays and Multiple Parameters for Optimal Diagnosis of Lyme Neuroborreliosis in a Routine Clinical Setting

Author(s) -

Tamara van Gorkom,

Willem Voet,

Gijs H. J. van Arkel,

Michiel Heron,

B. J. A. Hoeve-Bakker,

Daan W. Notermans,

Steven Thijsen,

Kristin Kremer

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.00061-22

Subject(s) - neuroborreliosis , lyme neuroborreliosis , serology , lyme disease , medicine , retrospective cohort study , borrelia , borrelia burgdorferi , virology , immunology , pathology , antibody

The diagnosis of LNB is established by clinical symptoms, pleocytosis, and proof of intrathecal synthesis ofBorrelia -specific antibodies. Laboratory diagnosis of LNB is challenging, and validated diagnostic algorithms are lacking.

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