Open AccessComprehensive Analysis of the Nocardia cyriacigeorgica Complex Reveals Five Species-Level Clades with Different Evolutionary and Pathogenicity Characteristics
Author(s) -
Shuai Xu,
Ming Wei,
Gang Li,
Zhenpeng Li,
Yanlin Che,
Lichao Han,
Wei Jia,
Fang Li,
Dan Li
Publication year - 2022
Publication title -
msystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.931
H-Index - 39
ISSN - 2379-5077
DOI - 10.1128/msystems.01406-21
Subject(s) - clade , biology , pathogenicity , nocardia , genus , microbiology and biotechnology , zoology , evolutionary biology , phylogenetics , bacteria , genetics , gene
Nocardia species are opportunistic bacterial pathogens that can affect all organ systems, primarily the skin, lungs, and brain.N. cyriacigeorgica is the most prevalent species within the genus, exhibits clinical significance, and can cause severe infections when disseminated throughout the body. However, the evolution, diversity, and pathogenicity ofN. cyriacigeorgica remain unclear.