Open AccessIn-Depth Analysis of Bacillus anthracis 16S rRNA Genes and Transcripts Reveals Intra- and Intergenomic Diversity and Facilitates Anthrax Detection
Author(s) -
Peter Braun,
Fee Zimmermann,
Mathias C. Walter,
Sonja Mantel,
Karin Aistleitner,
Inga Stürz,
Gregor Grass,
Kilian Stoecker
Publication year - 2022
Publication title -
msystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.931
H-Index - 39
ISSN - 2379-5077
DOI - 10.1128/msystems.01361-21
Subject(s) - bacillus anthracis , biology , genetics , 16s ribosomal rna , ribosomal rna , gene , genome , microbiology and biotechnology , bacteria
For severe infectious diseases, precise pathogen detection is crucial for antibiotic therapy and patient survival. Identification ofBacillus anthracis , the causative agent of the zoonosis anthrax, can be challenging when querying specific nucleotide sequences such as in small subunit rRNA (16S rRNA) genes, which are commonly used for typing of bacteria.