Open AccessA Dual-Functional Orphan Response Regulator Negatively Controls the Differential Transcription of Duplicate groEL s and Plays a Global Regulatory Role in Myxococcus
Author(s) -
Zhuo Li,
Tian-yu Wan,
Zhuo Pan,
Jianing Wang,
Duohong Sheng,
Yuezhong Li
Publication year - 2022
Publication title -
msystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.931
H-Index - 39
ISSN - 2379-5077
DOI - 10.1128/msystems.01056-21
Subject(s) - myxococcus xanthus , biology , transcription factor , genetics , response regulator , regulator , regulation of gene expression , transcription (linguistics) , gene , transcriptional regulation , repressor , regulatory sequence , microbiology and biotechnology , mutant , linguistics , philosophy
Multiply copiedgroEL s require precise regulation of transcriptions for their divergent cellular functions. Here, we reported that an orphan response regulator (RR) tunes the transcriptional discrepancy of the duplicategroEL s inMyxococcus xanthus DK1622 in a dual-functional mode.