Open AccessLife Cycle Stage-Specific Accessibility of Leishmania donovani Chromatin at Transcription Start Regions
Author(s) -
Janne Grünebast,
Stephan Lorenzen,
Julia Zummack,
Joachim Clos
Publication year - 2021
Publication title -
msystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.931
H-Index - 39
ISSN - 2379-5077
DOI - 10.1128/msystems.00628-21
Subject(s) - biology , euchromatin , chromatin , heterochromatin , genetics , epigenetics , transcription (linguistics) , gene , microbiology and biotechnology , linguistics , philosophy
Leishmania parasites are important pathogens with a global impact and cause poverty-related illness and death. They are devoid of classiccis - andtrans -acting transcription regulators but use regulated translation and gene copy number variations to adapt to hosts and environments.