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Proposed Changes to U.S. Policy on Potential Pandemic Pathogen Oversight and Implementation
Author(s) -
Thomas V. Inglesby,
Marc Lipsitch
Publication year - 2020
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00990-19
Subject(s) - biosecurity , biosafety , transparency (behavior) , government (linguistics) , pandemic , work (physics) , covid-19 , political science , public administration , business , public relations , infectious disease (medical specialty) , medicine , engineering , biology , law , disease , microbiology and biotechnology , mechanical engineering , linguistics , philosophy , pathology
We propose here changes to the U.S. government policy on potential pandemic pathogen (PPP) oversight and implementation, emphasizing transparency of the review process and the content of the review, publication of the review in advance, responsible publication of enhanced PPP research, high-level signoff on approvals of enhanced PPP experiments, and the need for a significant effort to establish a common international approach to enhanced PPP work. We advocate that the U.S. government recommend, and non-U.S. government funders and journals adopt, a set of best practices that would extend important considerations of biosafety and biosecurity to all work on enhanced potential pandemic pathogens regardless of funding source.

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