Open AccessOptiFit: an Improved Method for Fitting Amplicon Sequences to Existing OTUs
Author(s) -
Kelly L. Sovacool,
Sarah L. Westcott,
Michael B. Mumphrey,
Gabrielle A. Dotson,
Patrick D. Schloss
Publication year - 2022
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00916-21
Subject(s) - amplicon , computer science , amplicon sequencing , computational biology , biology , genetics , polymerase chain reaction , gene , 16s ribosomal rna
Advancements in DNA sequencing technology have allowed researchers to affordably generate millions of sequence reads from microorganisms in diverse environments. Efficient and robust software tools are needed to assign microbial sequences into taxonomic groups for characterization and comparison of communities.
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