Comparison of Methods To Collect Fecal Samples for Microbiome Studies Using Whole-Genome Shotgun Metagenomic Sequencing | Zendy

Doratha A. Byrd | Zendy; Rashmi Sinha | Zendy; Kristi L. Hoffman | Zendy; Jun Chen | Zendy; Xing Hua | Zendy; Jianxin Shi | Zendy; Nicholas Chia | Zendy; Joseph F. Petrosino | Zendy; Emily Vogtmann | Zendy

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Comparison of Methods To Collect Fecal Samples for Microbiome Studies Using Whole-Genome Shotgun Metagenomic Sequencing

Author(s) -

Doratha A. Byrd,

Rashmi Sinha,

Kristi L. Hoffman,

Jun Chen,

Xing Hua,

Jianxin Shi,

Nicholas Chia,

Joseph F. Petrosino,

Emily Vogtmann

Publication year - 2020

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.00827-19

Subject(s) - metagenomics , microbiome , shotgun sequencing , biology , computational biology , feces , shotgun , genome , bioinformatics , genetics , microbiology and biotechnology , gene

A major direction for future microbiome research is implementation of fecal sample collections in large-scale, prospective epidemiologic studies. Studying microbiome-disease associations likely requires microbial data to be pooled from multiple studies. Our findings suggest collection methods that are most optimal to be used standardly across future WGSS microbiome studies.

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