Open AccessCharacterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine
Author(s) -
Aditi Sharma,
Michael A. Zeller,
Carine K. Souza,
Tavis K. Anderson,
Amy L. Vincent,
Karen M. Harmon,
Ganwu Li,
Jianqiang Zhang,
Phillip C. Gauger
Publication year - 2022
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00809-21
Subject(s) - virology , biology , neuraminidase , virus , influenza a virus , hemagglutinin (influenza) , pandemic , reassortment , covid-19 , medicine , disease , pathology , infectious disease (medical specialty)
H3.2010.2 is a new phylogenetic clade of H3N2 circulating in swine that became established after the spillover of a human seasonal H3N2 from the 2016–2017 influenza season. The novel H3.2010.2 transmitted and adapted to the swine host and demonstrated reassortment with internal genes from strains endemic to pigs, but it maintained human-like HA and NA.