Open AccessGastric Non-Helicobacter pylori Urease-Positive Staphylococcus epidermidis and Streptococcus salivarius Isolated from Humans Have Contrasting Effects on H. pylori-Associated Gastric Pathology and Host Immune Responses in a Murine Model of Gastric Cancer
Author(s) -
Zeli Shen,
JoAnn Dzink-Fox,
Yan Feng,
Sureshkumar Muthupalani,
Anthony Mannion,
Alexander Sheh,
Mark T. Whary,
Hilda Holcombe,
Blanca Piazuelo,
Luis Eduardo Bravo,
Christine Josenhans,
Sebastian Suerbaum,
Keith T. Wilson,
Richard M. Peek,
Yichen Wang,
James G. Fox
Publication year - 2022
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00772-21
Subject(s) - streptococcus salivarius , helicobacter pylori , immune system , cancer , immunology , microbiology and biotechnology , staphylococcus epidermidis , urease , biology , medicine , streptococcus , staphylococcus aureus , gastroenterology , bacteria , enzyme , genetics , biochemistry
Chronic infection withH. pylori is the main cause of gastric cancer, which is a global health problem. In two Colombian populations with high levels ofH. pylori prevalence, the regional gastric cancer rates are considerably different.