Open AccessmSphere of Influence: Considering Complex Mutational Processes That Shape Microbial Virulence
Author(s) -
Matthew Anderson
Publication year - 2019
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00578-19
Subject(s) - candida albicans , biology , virulence , context (archaeology) , microbiology and biotechnology , genetics , gene , phenotype , fungal pathogen , pathogen , adaptation (eye) , paleontology , neuroscience
Matt Anderson works in the field of genetics and infectious disease, with a focus on the human fungal pathogen Candida albicans In this mSphere of Influence article, he reflects on how two papers, "Gene Flow Contributes to Diversification of the Major Fungal Pathogen Candida albicans " (J. Ropars, C. Maufrais, D. Diogo, M. Marcet-Houben, A. Perin, et al., Nat Commun 9:2253, 2018, https://doi.org/10.1038/s41467-018-04787-4) and "Selection of Candida albicans Trisomy during Oropharyngeal Infection Results in a Commensal-Like Phenotype" (A. Forche, N. V. Solis, M. Swidergall, R. Thomas, A. Guyer, et al., PLoS Genet 15:e1008137, 2019, https://doi.org/10.1371/journal.pgen.1008137), made an impact on him by incorporating less commonly investigated mechanisms of genome evolution into the context of microbial adaptation.