Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development | Zendy

Fikri Y. Avci | Zendy; Francesco Berti | Zendy; Peter Dull | Zendy; John P. Hennessey | Zendy; Viliam Pavliak | Zendy; A. Krishna Prasad | Zendy; Willie F. Vann | Zendy; Michael Wacker | Zendy; Olivier Marcq | Zendy

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Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

Author(s) -

Fikri Y. Avci,

Francesco Berti,

Peter Dull,

John P. Hennessey,

Viliam Pavliak,

A. Krishna Prasad,

Willie F. Vann,

Michael Wacker,

Olivier Marcq

Publication year - 2019

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.00520-19

Subject(s) - glycoconjugate , key (lock) , immunology , medicine , biology , computer science , bioinformatics , computer security

Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic. The lack of fundamental understanding of factors controlling clinical efficacy of glycoconjugate vaccines is discussed while key parameters demanding focused and collaborative research are identified.

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