Open AccessProgression of SARS-CoV-2 Seroprevalence in St. Louis, Missouri, through January 2021
Author(s) -
Brian Smith,
Andrew B. Janowski,
Arim C Fremont,
Lucas J. Adams,
Ya-Nan Dai,
Christopher W Farnsworth,
Ann M. Gronowski,
Stephen M. Roper,
David Wang,
D.H. Fremont
Publication year - 2021
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.00450-21
Subject(s) - seroprevalence , medicine , pandemic , covid-19 , vaccination , demography , outbreak , pediatrics , antibody , serology , virology , immunology , disease , infectious disease (medical specialty) , sociology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity was assessed for 3,066 individuals visiting hospitals in St. Louis, Missouri, during July 2020, November 2020, or January 2021. Seropositivity in children increased from 5.22% in July to 21.16% in January. In the same time frame, seropositivity among adults increased from 4.52% to 19.03%, prior to initiation of mass vaccination. IMPORTANCE This study determined the percentage of children and adult samples from the St. Louis metropolitan area in Missouri with SARS-CoV-2 antibodies during three collection periods spanning July 2020 to January 2021. By January 2021, 20.68% of the tested individuals had antibodies. These results show the evolution of the SARS-CoV-2 pandemic in St. Louis, Missouri, and provide a snapshot of the extent of infection just prior to the start of mass vaccination.